I just got an email update from MDLinx about the following article. This is only a summary of the article. In order to read the whole thing you have to pay $32 I think. The source link is included at the end of the article summary if you're interested in purchasing it:
Pain, 04/04/2012
Cuatrecasas G et al. – In this largest and longest placebo–controlled trial
performed in FM (NCT00933686), addition of growth hormone (GH) to the standard
treatment is effective in reducing pain, showing sustained action over time.
Methods
- A total of 120 patients were enrolled in a multicenter, placebo–controlled
study for 18months.
- They were randomly assigned to receive either 0.006mg/kg/day of GH
subcutaneously (group A, n=60) or placebo (group B, n=60) for 6months (blind
phase).
- The placebo arm was switched to GH treatment from month 6 to month 12 (open
phase), and a follow–up period after GH discontinuation was performed until
month 18.
- Standard treatment for fibromyalgia (selective serotonin re–uptake
inhibitors, opioids, and amitriptyline) was maintained throughout the study.
- Number and intensity of tender points, Fibromyalgia Impact Questionnaire
(FIQ) with its subscales, and EuroQol 5 dimensions test (EQ5D) with visual
analogue scale (VAS) were assessed at different time points.
Results
- At the end of the study, 53% of group A patients obtained fewer than 11
positive tender points, vs 33% of group B patients (P<.05). 39.1% vs 22.4%
reached more than 50% improvement in VAS (P<.05).
- Group A patients showed significantly improved FIQ scores
(P=.01) compared with group B.
- Although GH discontinuation worsened all scores in both groups during
follow–up, impairment in pain perception was less pronounced in the GH–treated
group (P=.05).
Read more:
http://www.mdlinx.com/pain-management/news-article.cfm/4003919/fibromyalgia#ixzz1vWoGSN3f
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